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48 | 3 | 21 Transfusion Medicine and Hemotherapy Interdisciplinary Journal for Transfusion Medicine, Hemotherapy, Immunohematology, and Clinical Hemostasis Focus COVID-19 Editors W. Korte (St. Gallen), P. Schlenke (Graz)
Transfusion Medicine
and Hemotherapy
Founded in 1973 as «Die Infusionstherapie» by H. Reissigl, H. Grobecker, U. Henneberg, K.H. Bäßler
Continued by: H.-D. Viering (1973–1977), A. Grünert (1982–1992), G. Kleinberger (1982–1988),
K. Widhalm (1988–1992), G. Wolfram (1990–1992), J. Eckart (1992–1997), H. Forst (1992–1997),
K. Meßmer (1992–1997), K. Peter (1992–1997), K.H. Usadel (1992–1997), B. Zwißler (1995–1997),
K. Gutensohn (1998–2001), V. Kretschmer (1990–2002), W. Stangel (1992–2005),
W. Dzik (1998–2005), H.G. Klein (1998–2005), W. Sibrowski (2003–2014)
Editor-in-Chief
Peter Schlenke, MD – Department of Blood Group Serology and Transfusion Medicine, Medical
University of Graz, Graz, Austria
Associate Editors
Official Organ of Peter Bugert, PhD – Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim,
Heidelberg University, Mannheim, Germany
German Society for Transfusion Medicine Andreas Buser, PhD – Blutspendezentrum SRK beider Basel, Basel, Switzerland
and Immunohematology Britta Eiz-Vesper, MD – Institute for Transfusion Medicine, Hanover Medical School, Hanover,
Germany
Beat M. Frey, MD – Blood Transfusion Service Zürich, SRC, Schlieren, Switzerland
Christoph Gassner, PhD – Independent Researcher, Zurich, Switzerland
Hans-Gert Heuft, MD – Institute for Transfusion Medicine and Immunehematology with Blood Bank
Diagnostics, University Hospital Magdeburg, Magdeburg, Germany
Andreas Humpe, MD – Department of Anesthesiology, Grosshadern Medical Center of the
Deutsche Gesellschaft für Transfusions- Ludwig-Maximilian University, Munich, Germany
medizin und Immunhämatologie David Juhl, MD – Institute of Transfusion Medicine, University Hospital of Schleswig-Holstein,
Lübeck, Germany
Wolfgang Korte, MD –Center for Laboratory Medicine, St. Gallen, Switzerland
Beate Mayer, MD – Institute of Transfusion Medicine, Charité – Universitätsmedizin Berlin,
Berlin, Germany
Axel Pruß, MD – Institute of Transfusion Medicine, Charité – Universitätsmedizin Berlin,
Berlin, Germany
Thomas Thiele, MD – Institute of Immunology and Transfusion Medicine, Department of
Transfusion Medicine, University Medical Center Greifswald, Greifswald, Germany
Franz F. Wagner, MD – Institute Springe, German Red Cross Blood Service NSTOB, Springe, Germany
Patrick Wuchter, PhD – Institute of Transfusion Medicine and Immunology, Medical Faculty
Mannheim, University of Heidelberg, Mannheim, Germany
Editorial Board Members
Jason Acker, PhD – Department of Laboratory Medicine and Pathology, University of Alberta,
Edmonton, AB, Canada
Karina Althaus, MD – Center for Clinical Transfusion Medicine, University Hospital of Tübingen and
German Red Cross Blood Donation Service Baden-Wuerttemberg-Hessen, Tübingen, Germany
Tamam Bakchoul, MD – Center for Clinical Transfusion Medicine, University Hospital of Tübingen and
German Red Cross Blood Donation Service Baden-Wuerttemberg-Hessen, Tübingen, Germany
(Continued on next page)
Printed in Germany on acid-free and non-aging paper
(ISO 9706) by Printec Offset, medienhaus, Kassel(Continued)
Gregor Bein, MD – Institute for Clinical Immunology and Transfusion Medicine,
Justus Liebig University, Gießen, Germany
Reinhard Burger, MD – Robert Koch Institute, Berlin, Germany
Jürgen Bux, MD – German Red Cross Blood Donation Service West, Hagen, Germany
Toni Cathomen, PhD – Institute for Transfusion Medicine and Gene Therapy, University of Freiburg,
Freiburg, Germany
Jens Dreier, PhD – Institute for Laboratory and Transfusion Medicine, Heart and Diabetes Center
North Rhine-Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany
Hermann Eichler, MD – Institute of Clinical Hemostaseology and Transfusion Medicine,
Saarland University Medical Center, Homburg/Saar, Germany
Birgit Gathof, MD – Institute for Transfusion Medicine, University Hospital Cologne, Cologne,
Germany
Holger Hackstein, MD – Institute for Transfusion Medicine and Hemostaseology, University Hospital
Erlangen, Erlangen, Germany
Reinhard Henschler, PhD –Institute for Transfusion Medicine, University Hospital Leipzig, Leipzig,
Germany
Holger Hennig, MD – Institute of Transfusion Medicine, University Hospital of Schleswig-Holstein,
Lübeck, Germany
Volker Kiefel, MD – Institute for Transfusion Medicine, Rostock University Medical School,
Rostock, Germany
Harald Klüter, MD – Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim,
University of Heidelberg, Mannheim, Germany
Behrouz Mansouri Taleghani, MD – University Clinic of Hematology and Central Hematology
Laboratory, Bern University Hospital, Inselspital, Bern, Switzerland
Jens Meier, MD – Department of Anesthesiology and Critical Care Medicine, Kepler University
Hospital, Med Campus III, Linz, Austria
Rainer Moog, MD – German Red Cross Blood Donor Service North-East, Institute Cottbus,
Cottbus, Germany
Andrew D. Mumford, PhD – Bristol CardioVascular, University of Bristol, Bristol, United Kingdom
Christoph Niederhauser, PhD – Interregional Blood Transfusion SRC Ltd. Bern, Bern, Switzerland
Ruth Offergeld, MD – Robert Koch Institute, Berlin, Germany
Thierry Peyrard, PhD – National Institute of Blood Transfusion (INTS), Paris, France
Katharina Schallmoser, PhD – Blood Group Serology and Transfusion Medicine, Paracelsus Medical
University (PMU) Salzburg, Salzburg, Austria
Erwin Strasser, MD – Department of Transfusion Medicine & Haemostaseology, University Hospital
Erlangen, Erlangen, Germany
Jean-Daniel Tissot, MD – Interregional Blood Transfusion, Lausanne, Switzerland
Torsten Tonn, MD – Institute for Transfusion Medicine Dresden, German Red Cross Blood Donation
Service North/East, Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany
Pieter F. van der Meer, PhD – Department of Product and Process Development, Sanquin Blood Bank,
Amsterdam, The Netherlands
Nina Worel, MD – Department for Blood Group Serology and Transfusion Medicine,
Medical University of Vienna, Vienna, Austria
Mark H. Yazer, MD – Department of Pathology, University of Pittsburgh School of Medicine,
Pittsburgh, PA, USA
Malte Ziemann, MD – Institute of Transfusion Medicine, University Hospital of Schleswig-Holstein,
Lübeck, GermanyA
© 2021 S. Karger AG, Basel
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HEALTHCAREVol. 48, No. 3, 2021
Contents
Research Articles
137 Donors for SARS-CoV-2 Convalescent Plasma for a Controlled Clinical Trial:
Donor Characteristics, Content and Time Course of SARS-CoV-2 Neutralizing
Antibodies
Körper, S.; Jahrsdörfer, B. (Ulm); Corman, V.M. (Berlin); Pilch, J. (Homburg);
Wuchter, P. (Mannheim); Blasczyk, R. (Hannover); Müller, R. (Mannheim); Tonn, T.
(Dresden); Bakchoul, T. (Tübingen); Schäfer, R. (Frankfurt); Juhl, D. (Lübeck);
Schwarz, T. (Berlin); Gödecke, N. (Hannover); Burkhardt, T. (Dresden); Schmidt, M.
(Frankfurt); Appl, T. (Ulm); Eichler, H. (Homburg); Klüter, H. (Mannheim); Drosten, C.
(Berlin); Seifried, E. (Frankfurt); Schrezenmeier, H. (Ulm)
Focus Article
148 Effect of Methylene Blue Pathogen Inactivation on the Integrity of
Immunoglobulin M and G
Raster, J.; Zimmermann, K.; Wesche, J.; Aurich, K.; Greinacher, A.; Selleng, K.
(Greifswald)
Focus Article
154 Detectable SARS-CoV-2 RNAemia in Critically Ill Patients, but Not in
Mild and Asymptomatic Infections
Richter, E. (Bonn); Al Arashi, D. (Heinsberg); Schulte, B.; Bode, C.; Marx, B.;
Aldabbagh, S.; Schlüter, C.; Kümmerer, B.M.; Oldenburg, J. (Bonn); Funk, M.B.
(Langen); Putensen, C.; Schmithausen, R.M.; Hartmann, G.; Eis-Hübinger, A.;
Streeck, H. (Bonn)
Focus Article
161 Relationship of SARS-CoV-2 Pandemic with Blood Groups
Yanardag Acik, D.; Bankir, M. (Adana)
Focus Article
Case Report
168 Monitoring of COVID-19-Associated Coagulopathy and Anticoagulation
with Thromboelastometry
Katz, D.; Maher, P.; Getrajdman, C.; Hamburger, J.; Zhao, S.; Madek, J.; Bhatt, H.;
Levin, M. (New York, NY); Görlinger, K. (Essen/Munich)
Focus Article
Cover illustration
© okapia.de
© 2021 S. Karger AG, Basel
www.karger.com
karger@karger.comLetter to the Editor
173 Neutralizing Antibodies against SARS-CoV-2 and HLA Class I and II
Polymorphism
Weidner, L.; Kalser, J.; Kreil, T.R.; Jungbauer, C.; Mayr, W.R. (Vienna)
Focus Article
Research Articles
175 Population-Based Analysis of the Impact of Demographics on the Current
and Future Blood Supply in the Saarland
Eichler, H.; Feyer, A.K. (Homburg); Weitmann, K.; Hoffmann, W. (Greifswald);
Henseler, O. (Langen); Opitz, A. (Bad Kreuznach); Patek, A. (Saarbrücken); Hans, D.N.
(Merzig); Schönborn, L.; Greinacher, A. (Greifswald)
183 Ethical Issues and Management of Fetal Hemolytic Anemia Caused by
Anti-Rh17 in a Multipara with Rare –D– Phenotype
Torreiter, P.P.; Macher, S.; Matzhold, E.-M.; Resch, B.; Klaritsch, P. (Graz);
Körmöczi, G.F. (Vienna); Polin, H. (Linz); Neuhold, L. (Graz); Schönbacher, M.
(Vienna); Schlenke, P.; Wagner, T. (Graz)
188 Factors Associated with Intention to Donate Hematopoietic Stem Cells
among Blood Donors
Ting, C.Y. (Kuching/Kota Samarahan); Lee, Y.F. (Geneva/Putrajaya); Lim, C.J.
(Singapore); Ting, R.S.K. (Selangor); MD Zahrin, M.M. (Kuching); Ahmad, A.S. (Sibu);
Wong, J.S.Y. (Miri); Arip, M.; Zakaria, Z. (Kuala Lumpur); Ahmad Zaidi Adruce, S.;
Tnay, J.K.S. (Kota Samarahan); Wong, Y.S. (Kuching)
Letters to the Editor
196 Regarding Microbiological Control of Cellular Products: The Relevance of
the Cellular Matrix, Incubation Temperature, and Atmosphere for the
Detection Performance of Automated Culture Systems [Transfus Med
Hemother. 2020;47:254–63]
Moog, R. (Cottbus)
198 Response to Regarding Microbiological Control of Cellular Products:
The Relevance of the Cellular Matrix, Incubation Temperature, and
Atmosphere for the Detection Performance of Automated Culture Systems.
Transfus Med Hemother. 2020;47:254–63
Günther, F. (Heidelberg/Marburg)
200 PharmaNews
© 2021 S. Karger AG, Basel
www.karger.com
karger@karger.comJournal Information
Aims and Scope
This journal is devoted to all areas of transfusion medicine. These include the quality and
security of blood products, therapy with blood components and plasma derivatives, trans-
fusion-related questions in transplantation, stem cell manipulation, therapeutic and diag-
nostic problems of hemostasis, immuno-hematological investigations, and legal aspects of
the production of blood products as well as hemotherapy. Both comprehensive reviews and
Guidelines for Authors primary publications that detail the newest work in transfusion medicine and hemotherapy
We strongly encourage authors to read
the Guidelines for Authors at
promote the international exchange of knowledge within these disciplines. Consistent with
www.karger.com/tmh_guidelines prior to this goal, continuing clinical education is also specifically addressed.
submitting an article.
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the persons responsible who can be found at
http://www.karger.com/Journal/Contact/224170.
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Publication Data: Transfusion Medicine and Hemo- methods, instructions or products referred to in the
therapy is published 7 times a year. Volume 48 with content or advertisements.
6 issues appears in 2021.
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