Produktübersicht Mikrobiologie - Ein ausgewähltes Sortiment an Geräten und Verbrauchsmaterialien für das Mikrobiologische Labor Zu allen Produkten ...
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Produktübersicht
Mikrobiologie
Ein ausgewähltes Sortiment an Geräten und
Verbrauchsmaterialien für das Mikrobiologische Labor
Zu allen Produkten bieten wir Applikationssupport,
Beratung sowie umfangreiche
Service- und Garantieleistungen
Mikrobiologie Mikrobiologie IUL Kolonienzähler AID Serielle Verdünnung Lab Robot Mikrobiologie Interscience Schwingquarzsensoren (QCM-D) 3T analytik Schüttler Diverse Trockenschränke / Inkubatoren MMM Medcenter CO2 Inkubatoren NBS - MMM - Binder Werkbänke Baker Ruskinn Anoxomat III - vollautom. Anaerobier System Advanced Ultratiefkühlgeräte New Brunswick Scientific Lager- und Ordnungssysteme National Lab Verbrauchsmaterial aus Kunststoff Sterilin Laborzubehör THOMAPLAST I Reichelt Nährkartonscheiben Dr. Möller & Schmelz Mikrobiologische Testplatten Charm PCR-Schnelltest-Diagnostik Biomed EliSpot- FluoroSpot Reader AID ELISPOT und PCR Kits AID
Mikrobiologie
Mikrobiologie
Die IUL Produktpalette für die mikrobiologische
Lebensmittelanalytik umfasst die Probenvorbereitung,
Homogenisation, automatische Ausplattierung und das
Zählen der Kolonien inkl. dem dazugehörenden
Verbrauchsmaterial.
Gravimetrische Verdünner (Delta und Smart Dilutor)
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Homogenisatoren (Mastikator)
Spiralplattierer (Eddy Jet)
Manuelle und automatische Kolonienzähler (Haloes Counter, Colony
Counter, Flash & Go)
Airsampler, Polystainer
Kolonienzähler
Eine Komplettlösung zur Analyse von bis zu 200
Agarplatten pro Stunde.
BacSpot Reader manuell: Gerät für die Auszählung von Petrischalen
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BacSpot Reader Roboter: Vollautomatischer Kolonienzähler inkl. Barcode
Printer
Serielle Verdünnung
Der schnellste und günstigste Weg zur seriellen
Verdünnung. Einfache Bedienung des Shakers über
optischen Sensor. Einfache Handhabung: Nur Öffnen der
Cups und verdünnen.
Dilushaker (6 verschiedene Modelle)
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Dilucups (gefüllt mit MRD, Peptonwasser, physiologischer NaCl-Lösung oder
Befüllung auf Kundenwunsch)
Keine gekühlte Lagerung nötig (Haltbarkeit 18 Monate), kein Autoklavieren,
kein Abwaschen von verschmutzen RG's
30.04.2019 Seite 1
Mikrobiologie
Mikrobiologie
Interscience bietet High-End-Produkte für die
mikrobiologische Lebensmittelanalytik aus den Bereichen
Probenvorbereitung, Homogenisation, automatische
Ausplattierung und automatisches Kolonienzählen.
Gravimetrische Verdünner
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Homogenisatoren (Bag Mixer)
Spiralplattierer (EasySpiral)
Manuelle und automatische Kolonienzähler (Scan 100, Scan 300, Scan 500,
Scan 1200)
Grosse Palette an Filterbeuteln
Schwingquarzsensoren (QCM-D)
“label-freie” Erforschung und Analyse von molekularen
Bindungen & Interaktionen und elektrochem
Phänomenen auf Basis von Schwingquarzsensoren (QCM-
D).
QCM Quarzsensor Instrumente QCELL/QCELL T (auch voll automatisiert)
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Sehr einfache Handhabung
Benutzerfreundliche Software
Schüttler
Die IGZ Schüttler-Produktpalette reicht vom preiswerten
Benchtop-Gerät über mehr als 70 zum Teil hoch
spezialisierte Modelle, wie dem Ultraschallbadschüttler
bis zum "High-End" Schüttler.
NBS: Innova, Excella und C/I-Reihe
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Stuart: Schüttler, Roller, Rotatoren, Vortex Mixer, Rührer
IKA: Vortex Mixer, Lab dancer, Benchtop Schüttler, Schüttler für
Mikrotitterplatten
Biosan: Vortex Mixer, Schüttler mit verstellbarer Schüttelrichtung, Rotatoren
Bandelin: Kombination von Schüttler und Ultraschallbad
30.04.2019 Seite 2
Mikrobiologie
Trockenschränke / Inkubatoren
MMM bietet ein preiswertes Sortiment vom einfachen
Trockenschrank bis zum Vakuumtrockenschrank an. Der
Temperaturbereich geht von 5°C über Raumtemperatur
bis 250°C.
Ecocell-Serie von 22 bis 707L
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Durocell-Serie von 22 bis 222L mit hochresistenter EPLON Beschichtung
Venticell-Serie von 22 bis 707L mit forcierter Umluft
Stericell-Serie von 22 bis 404L zur Sterilisation
Vacucell-Serie von 22 bis 111L mit Vakuum
CO2 Inkubatoren
Die IGZ führt ein grosses Sortiment an Geräten von 14 -
170L Inhalt. Das Sortiment geht von einfachen und
günstigen Geräten bis hin zu High End Geräten mit
verschiedenen Zusatzfunktionen.
NBS: Galaxy CO2-Inkubatoren S- und R-Reihe 14 bis 170L
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MMM: CO2Cell-Reihe mit Geräten zu 48 und 170L Volumen
Binder: CB-Serie 150 und 210L
Werkbänke
Die Ruskinn Concept Serie wurde speziell zur
Kultivierung von Bakterien im anaeroben oder
mikroaerophilen Klima entwickelt.
Bug Box (kleine Kammer für bis zu 300 Petrischalen)
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Bug Box Plus (Kammer mit breiter Schleuse)
Concept 400 (Kammer für bis zu 620 Petrischalen)
Concept Plus (Kammer für bis zu 740 Petrischalen)
Concept 1000 (Kammer für bis zu 1200 Petrischalen)
30.04.2019 Seite 3
Mikrobiologie
Anoxomat III - vollautom. Anaerobier System
Der Anoxomat III arbeitet nach dem Evakuation-
Austausch Prinzip von McIntosh/Fildes um anaerobe,
mikroaerophile oder kapnophile Milieus zu erzeugen.
Schnelles und gutes Koloniewachstum
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Einfach zu bedienendes, platzsparendes Design mit Touchscreen
Ökonomisch und ökologisch - keine Gaspacks und Kontrollstreifen notwendig
Automatische Kontrolle der Gaszufuhr und Katalysatoren-Aktivität
Verschiedene Topfgrössen erhältlich - für kleine bis grössere Labors geeignet
Ultratiefkühlgeräte
Die IGZ Freezerpalette umfasst grossvolumige Schränke
und Truhen, Kleinstfreezer sowie Lagersysteme.
NBS: Schränke -86°C, 101L - 725L (U360 extra schmales Modell), Truhen -
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86°C, 340L - 760L HEV (High Efficient Freezers) und CryoCube Modelle mit
ultrastarker Isolierung.
Binder: Ultra-Tiefkühlschränke für die Langzeitlagerung bei -86 °C UF V 500
und UF V 700
Lager- und Ordnungssysteme
Die National Lab Ordnungssysteme umfassen Racks in
jeder Grösse (auch Massanfertigung), Boxen für Eppis,
PCR-Röhrchen, Objektträger oder Zentrifugenröhrchen,
sowie Cryo-Röhrchen.
Freezer-Racks für Schränke und Truhen aus Edelstahl
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Kartonboxen in 5 verschiedenen Farben und verschiedenen Grössen
Polypropylenboxen in 10 Farben und mit alphanumerischer Fachcodierung
Polycarbonatboxen (Cryoboxen)
Edelstahl Schrankkästen ohne feste Einteilung zur Lagerung von Flaschen
usw.
30.04.2019 Seite 4
Mikrobiologie
Verbrauchsmaterial aus Kunststoff
Sterilin bietet eine breite Produktpalette an
Einwegartikeln aus Kunststoff für die Mikrobiologie,
Wasseranalytik und Molekularbiologie.
Petrischalen aller Art und Grössen
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96 well Platten verschiedenster Art
Steril verpackte Pipetten und Pipettenspitzen
Flaschen für die Wasseranalytik
Cryotubes und Eppendorftubes
Laborzubehör THOMAPLAST I
Reichelt Thomaplast bietet eine breite Produktpalette an
Laborzubehör vom Skalpell bis zum Messbecher, auch in
kleinen Mengen.
Behältnisse (Flaschen, Röhrchen, Dosen, Boxen, Kästen, Schüsseln, Schalen
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usw.)
Laborbesteck (Schaufeln, Löffel, Spatel, Pinzetten, Skalpelle)
Laborstopfen und -kappen
Arbeitshilfen (Siedesteine, Dichtwolle, Ringe, Kugeln usw.)
Laborschutz (Matten, Unterlagen, Handschuhe usw. )
Nährkartonscheiben
Möller & Schmelz bietet eine breite Produktpalette für die
Trinkwasser-, Getränke- (Mineralwasser, Tafelwasser,
Bier, Wein, Fruchtsäfte), Badewasser- und
Lebensmittelanalytik.
Nährkartonscheiben (32 Sorten)
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Fertignährböden
Kits zur Trink- und Mineralwasseranalyse
Speziell für die Schweiz: NKS zum Nachweis von Brettanomyces-Hefen
Geräte und Zubehör
30.04.2019 Seite 5
Mikrobiologie
Mikrobiologische Testplatten
Die stapelbaren Charm Peel Pates eignen sich zur
schnellen und einfachen selektiven Detektion von
Mikroorganismen.
Peel Plate AC für aerobe Keime
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Peel Plate CC für coliforme Keime
Peel Plate EB für Enterobacteriaceae
Peel Plate EC für E.coli und coliforme Keime
Peel Plate HET für heterotrophe Bakterien, Peel Plate YM für Hefe und
Schimmel YM
PCR-Schnelltest-Diagnostik
Das patentierte GenomEra CDX™ System bietet eine
kosteneffektive und einfache Lösung für die PCR-
Diagnostik von Infektionserregern im klinischen
Routinelabor.
Parallele Testung verschiedener Erreger inerhalb von 50 Minuten
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Hohe Sensitivität und Spezifität, Erregerspektrum wird kontinuierlich erweitert
Aktuelle Testpalette:
GenomEra CDX™ MRSA/MSSA, GenomEra CDX™ Clostridium difficile,
GenomEra CDX™ Gruppe B-Streptokokken
GenomEra CDX™ Mycobacterium tuberculosis, GenomEra CDX™
Streptococcus pneumoniae
EliSpot- FluoroSpot Reader
Reader für 96-well plates
EliSpot Reader Classic: basic 96-well plate EliSpot Reader
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vSpot Reader Spectrum, High resolution EliSpot/FluoroSpot Reader für
verschiedene Plattenformate
iSpot Reader Spectrum, The ultimate high resolution 96-well plate
EliSpot/FluoroSpot Reader
30.04.2019 Seite 6
Mikrobiologie
ELISPOT und PCR Kits
Die AID Diagnostik Kits zeichnen sich dadurch aus, dass
die zu analysierende DNA vor der Hybridisierung mittels
einer PCR vervielfältigt wird. Auf diese Weise ist es
möglich, selbst geringe DNA-Aufkommen sicher und
genau zu analysieren.
Borrelien ELISPOT: Anti-Borrelia burgdorferi-IgG - Immunoblot, Anti-Borrelia
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burgdorferi-IgM-Immunoblot, "Shared Epitope" und Lyme-Arthritis
MRSA combi: Nachweis von Staphylococcus aureus und gleichzeitige
Bestimmung der Makrolid-, Beta-Laktam-, Tetracyclin-, Aminoglycosid- und
Chinolon-Resistenzgene
HPV Easy-Screening: Nachweis von Humanen Papillomaviren und
Differenzierung nach "high risk" und "low risk" Genotypen sowie
Einzelnachweis von HPV 16 und 18
Cap Bakterien: der Nachweis der häufigsten Erreger bei einer CAP – Infektion
30.04.2019 Seite 7
Description Specialized piston structure
Fully autoclavable Spray Bottle for industrial use.
For Pharmaceutical production, QC testing and Clinical laboratory.
Features
Available chemicals
- Isopropyl alcohol - Ethanol
- Benzalkonium chloride 0.2% solution
- Alkyldiaminoethylglycine hydrochloride 0.2% solution
- Chlorhexidine gluconate 0.05% solution
- Acrinol 0.2% solution
- Iodine based disinfectant
Unavailable chemicals
- Cresol - Oxydol
- Sodium hypochlorine solution
Specification Order Information - Aldehyde-based disinfectant
Spray : 1 ml per trigger Part No. : 32526-003 - Organic solvent
Capacity : 500 ml Product : AC Spray Bottle #887 - Viscous liquid
Dimension : W125 x D100 x H 208 mm Qty per carton : 24 bottles
Material : Polypropylene
Instruments
smart solutions & service
IGZ Instruments AG Tel. +41 44 456 33 33
Räf felstrasse 32 Fax +41 44 456 33 30
CH – 8045 Zürich www.igz.ch igz@igz.chOrdering Information 1 2 3
®
1. SphereFlash® Colony Counter unit
Automatic Colony Counter &
(includes Colonies LITE software ) Inhibition Halos measurement
CAT. 90007000
2. Colony PRO software World-class software, uniform & reflection-free illumination
CAT. 90007001
3. Halos PRO software
CAT. 90007002
Technical data
Petri dish maximum usable diameter: 90mm Computer Requirements:
Computer interface: USB 3.0 Type-A socket
Mains AC adaptor Output: 12V DC 3.43A · Microsoft Windows® 7, 8.1,10
(x64 platforms).
Power Range: 90~264 VAC
· 1 free USB 3.0 Port.
Frequency Range_ 47~63Hz
· 8 Gigabytes of RAM memory.
Maximum Power:40W
· 100 Megabytes of free disk space
Overvoltage Category: II
and 100 Gigabytes for the Database
Air temperature 15-30ºC (59-86ºF)
(for 5000 results stored with images).
Relative humidity: 10-75% (non-condensing)
· FullHD screen (1920x1080px)
Altitude: Up to 2000m (6500ft)
recomended.
Place of operation: For indoor use only.
· 24’’ screen size recommended.
Frequency Range: 50-60Hz
· Microsoft Excel® 2007 or higher, 64 bits
Pollution level 2
to open exported Excel® files.
Dimensions: 288x220x371 mm (1.34x8.66x14.6 in)
· A virtual PDF printer to create PDF
Weight: 5,5Kg (12.13 lb)
reports.
Doc. No. 50007950-01
Specifications subject to change without notice. CAT. 90007000
ShpereFlash with Colony LITEsoftware
For more information visit us at:
www.iul-inst.com Instruments
smart solutions & service
IUL, S.A. Ciutat d’Asunción, 4 - 08030 Barcelona (Spain) I GZ Instruments AG Tel. +41 44 456 33 33
iul@iul-inst.com • T. +34 93 274 02 32 • F. +34 93 274 01 44 Räf felstrasse 32 Fax +41 44 456 33 30
CH – 8045 Zürich www.igz.ch igz@igz.ch www.iul-inst.comAudit Trail: Security-relevant chronological
Product Overview set of records that will provide documentary
evidence of the sequence of activities that
The SphereFlash® is an Automatic Colony Counter that meets all the requirements that may be
have affected at any time a specific
required in a modern microbiology laboratory.
operation or event in the SphereFlash®.
With its Colony Lite software version it performs the colony counting in a simple and reliable way
thanks to its world-class software and its patented built-in lightning system.
For more demanding users the software can be upgraded to Colonies PRO to increase its
capabilities, e.g. setting User’s Permission Levels, LIMS connectivity, Worksheets, Barcode
Reading, Reporting, Audit Trail, or CFR21 Part 11.
With the optional Halos PRO app, the Sphere Flash unit can be transformed to measure inhibition
halos accepting various circle approximation criteria to obtain the corresponding diameters of
virtual circle areas.
In all versions the lighting is done through LEDs that are oriented to the internal wall of a moving 6SKHUH)ODVK
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Report generation: Easy and automatic
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spheric chamber. The result is an unprecedented uniform and reflections-free illumination in a generation of result reports with customizable
colony counter device. 3ODWH,'
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layout to include your Company’s logo and/or
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Main Benefits
Scalability: Starting Colonies LITE software version (included with the unit) it can be
World-Class Software: Easy & intuitive yet a powerful software. Even in its LITE version it will independently upgraded to Colonies PRO or Halos PRO.
detect a wide range of colony types with minor or none user parametrization.
Reflections-Free Illumination: Its patentend spheric chamber eliminates reflections in both, Software Comparison Table Colonies PRO Halos PRO
Colonies LITE
colonies and Petri plate, and provides a unifrom illumination for an improved image capture Feature Cat.No. 90007003 Cat. No. 90007001 Cat. No. 90007002
that will lead to better, more reliable, and consistent results. Colony Counting
Inhibition Zones Measurement
Standard Methods
Methods Edition
Automatic Calibration & Verification
Users Management
Results Table Cusotomization
Worksheet Mode
Remote Input-Output Mode (LIMs)
Audit Trail
Report Generation
Reflections-Free Image
High-Troughput: A fast and powerful image precessing software together with an automatic
®
Image captured from a SphereFlash Image captured from a traditional counter closing of the spheric chamber allows minor user intervention and time optimisation. Large
amounts of plates can be accurely counted.Real-time incubator and colony counter The real-time revolution!
Over 35 years of microbiology expertise
World leader in automatic colony counters
MADE IN
Made in France in our R&D center & manufacturing plant FRANCEScanStation in brief: ®
1 incubator
100 Petri dishes capacity
+
1 robotic arm
transfers the Petri dishes
+
1 automatic colony counter
ultra-HD
ScanStation® is a real-time incubator and colony counting station centralizing incubation, detection and counting
of 100 Petri dishes simultaneously.
Principle
100 Petri dishes are counted every 30 minutes throughout the process. Colonies are detected & counted as soon
as they appear.
Incubation time: 3h 6h 8h
FIRST RESULTS
Results
3x sooner faster accurate
Results in 1/3 of the time of a traditional 100 Petri dishes are processed Colonies are detected before clus-
analysis: 8 h instead of 24 h. simultaneously: colony counting is tering or covering can occur, and are
done automatically during incubation. differenciated from writings and debris.
3PATENTS PENDING A revolutio
Rotating Petri
carousel
Record-breaking capacity
of 100 Petri dishes (ø 90 mm)
Insulated
panoramic window
Easy process monitoring
Thermoregulated
incubator
Peltier module ± 1 °C
refrigerated incubator
No compressor
Storage unit
For computer, UPS,
accessories
Easy installation
Simply plug in the 100-240V~
power cord.
4nary design
High speed robotic arm
Automated plate handling
from incubation to counting
Real-time bacterial growth
Touch screen with real-time video
of the process
24/7 operation
Ultra-HD camera
Reflection free LED lighting
5 megapixel CCD sensor
Pressure-sensitive gripper
Automatically adapts to right-side up
or upside down Petri dishes.
No settings
5Real-time bacterial growth
350 CFU
300
250
200
150
100
50
0
1h 2h 3h 4h 5h 6h 7h 8h 9h 10h 11h 1
h
24
78
CFU
8h
Total incubation First results
time (24 h)
Anticipated results Real-time control
Automation of colony counting during incubation saves Discover bacterial growth hour by hour and see the video during
time and allows earlier release of production batches. and after incubation with zoom, pause and replay features…
6Anticipated results Traditional
with ScanStation method results
Incubation
time
2h 13h 14h 15h 16h 17h 18h 19h 20h 21h 22h 23h 24h
Coliforms on VRBL agar incubated at 37 °C
Zoom Full traceability
Data is archived and available throughout incubation up
Zoom directly on the image to check the state of the
to final validation of the results.
colonies and closely study their development.
7Innovative features
Robotic architecture
The incubator includes a robotic architecture with a 100
Petri dish carousel, an ultra rigid robotic arm for more
accuracy and durability and an ultra-HD automatic colony
counter.
Pressure-sensitive gripper
This high precision gripper fits to the Petri dishes rightside
up or upside down, grabs them from the carousel and
moves them to the image capture zone every 30 minutes.
Incubator
Laminated
L
Lam
amin
inat
ated
ed and
a d te
tem
temperature
mpe
perat
atur
ure
regu
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regulated flow Pe
eltie
ier
Peltier with Peltier module
mo
odu ule
modules es
Peltier modules allow a temperature regulation of ± 1 °C,
low energy consumption, no fluid nor compressor.
8PATENTS PENDING
Ultra HD image
With white LED lighting and 5 million pixels, the ultra HD
camera enables accurate counting and detection of the
colonies from their early development.
Touch screen interface
Makes it easier to navigate through the software and gives
real time access to the Petri dish data.
Multi-batch
The loading of Petri dishes can be done at the beginning
or during the incubation.
Petri dish batches can be added at any point during the
process.
9Ground-breaking benefits
Sooner
3x Colonies are detected as the incubation starts, at an early stage of their development.
Results are accurately estimated 3 times earlier than a traditional process and
then validated at the end of the process.The full process is video- recorded.
This allows anticipated results and a faster production workflow.
Faster
ScanStation® is the first equipment that centralizes incubation and real
time colony counting. Automation of the routine steps of the analyses, with
automatic colony counting, allows reproducible and reliable results.
Data, including film and results, are archived and available anytime.
Accurate
Providing images of the colonies at an early stage makes the process much
more accurate than the traditional method. Colonies are video recorded and
counted before being covered or clustered, and debris, writing are ignored.
You can check, zoom, control and see the development of a colony anytime.
Non-proprietary consumables:
= keep your agar
ScanStation® is compatible with your analysis methods and agar. It integrates
perfectly in a classic analysis workflow. It's more efficient, without changing
your habits!
10Technical specifications
ScanStation®
Reference 439 100
Capacity 100 Petri dishes
Reading time in between each dish 30 mn
Petri dish size Ø 90 mm right-side up or upside down
Type of plating accepted Pour plate, surface
OVERVIEW
Loading Single or multi-batch
Camera resolution 5 megapixels
Interface 23 inch touch screen
Software ScanStation® software
Data export Excel™
Video player Play, zoom, pause, replay, during and after incubation
Included computer system PC Windows 10 desktop with Intel i7 processor
Incubation temperature From 10 °C to 45 °C
THERMAL SPECIFICA-
Accuracy of incubation temperature ± 1 °C in 9 points of the incubator
Recording of the temperature Every minute
TIONS
Heating and cooling technology Peltier elements, compressor free
External temperature From 18°C to 25°C
Max external humidity temperature 70 %
Max incubation time 10 days
LED internal light ✔
SPECIFICATIONS
Electronic locking door ✔
Pressure sensitive gripper ✔
Extra rigid mass aluminum plateform ✔
1 year warranty ✔
External dimensions (w x d x h) 136 x 83 x 91 cm
WEIGHT AND DIMENSIONS
External dimensions (handles dismantled - w x d x h) 136 x 78.9 x 91 cm
Height of the storage unit 67 cm
Total height with storage unit 151 cm
Weight of the ScanStation® 287 kg
Weight of the storage furniture 59 kg
Power 100-240V~ 50-60 Hz
Max power 2000 watts
Demos and training welcome : please contact us ! Certified production
Delivered with : computer with preset software, keyboard and mouse, user's manual. WEEE RoHS Product made for INTERSCIENCE
2002/96/EC 2002/95/EC MADE IN by Interlab, an ISO 9001 certified company.
FRANCE
Accessories
Stand for screen Storage furniture Uninterrupted Server Code reader
and keyboard power supply Increases performance Bar-code reader (1D)
Storage of the computer
For great ergonomics and accessories In case of power cut and data storage and datamatrix reader (2D)
Ref 439 110 Ref 439 120 Ref 439 140 Ref 439 150 Ref 439 170
115005 ScanStation_B 1017. Pictures and information in this brochure are not contractually binding. ScanStation® is a trademark. This document is the translation of the french brochure and is not contractually binding. INTERSCIENCE reserves the right to change or improve the specifications of its products without notice. Please visit www.interscience.com for current updates
INNOVATION GENERAL PUBLIC DESIGN OBSERVER INNOVATIVE COMPANIES
AWARD WINNER AWARD WINNER LABEL AWARD WINNER
(Productivity / R.O.I category) FORUM LABO exhibition 2017 2017 CCI / La Montagne 2017
FORUM LABO exhibition 2017
ScanStation® 100 ScanStation® 200 ScanStation® 300
Available soon…
and additional information. RCS 950 356 220 Versailles. INTERSCIENCE SARL F78860. Printed by Madanec..
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Sensor Instrument for
Surface Interaction Analysis
in Real Time
qCell / qCell T
Label-Free Observation of Molecular Interactions,
Surface Layer Systems and Fluid Properties.
Quartz Crystal Microbalance Sensor PlatformExplore Surface Interactions in a New Way of
Operational Ease and Versatility
The qCell / qCell T is a quartz sensor instrument (QCM) for gaining real time insights into
molecular interactions, biofilms, liquid properties and even the analysis of blood.
The qCell / qCell T has been designed for unique operational ease and very short time to result.
qCell T comprises a small volume flow cell on a high precision
and powerful Peltier driven temperature (T) control system
for cooling and heating, a thermostated sample holder and
an attached pump for liquid handling. qCell is an entry-level
version with identical features but without T control and no
integration of pump control. Sensor data acquisition, thermal
control and fully automated pump operation are all carried
out under the common user interface of qGraph software.
For a convenient surface coating by standard lab operations
and an easy insertion into the flow cell, the sensor quartz
comes mounted on a sensor sheet. Through an optical
window the quartz surface can be visually observed during
all situations of measurement. All surfaces in contact with
the sample solution are highly resistant to most chemicals.
QCM Principle and Measurement
Quartz sensors are highly sensitive to the mass and the In the figures below the graphs of frequency and damping
material properties of deposited molecular layers as well as of three characteristic examples are shown, respectively.
of the wetting liquids at their surface. Due to its sensitivity A thin, rigid layer (e.g. a thin protein layer or a thin metal
to mass, the technique is often referred to as Quartz Crystal layer) will cause a shift in frequency alone, without a change
Microbalance (QCM). The measuring principle of quartz in damping (1). A change of viscosity of purely Newtonian
sensor technique is based on the precise oscillation of the liquids (e.g. water, treacle, milk or fruit juice) will cause a
quartz sensors at their resonant frequency when an alter- decrease in frequency and an increase in damping, to equal
nating voltage is applied. Depositions at the surface or amounts (2). A viscoelastic layer (e.g. layers of polymers,
wetting of the surface result in a frequency shift and biofilms, bacteria or cells) results likewise in a frequency
– depending on the material properties – additionally in a and damping shift in opposite directions, but with different
damping of the oscillation. Both, the frequency shift and amplitudes (3). These examples reveal, that by analyzing
the damping (dissipation) of the oscillation are captured these graphs it becomes possible to determine properties as
with the qCell / qCell T instrument with high resolution viscosity (or shear module), mass or thickness of interfacial
and in real time. layers.
1 2 H2O 3
f [Hz] f [Hz] f [Hz]
rigid molecular layer
H2O + glycerol
sensor sensor sensor
time time D [Hz] time
D [Hz] D [Hz]
time time time
2qCell / qCell T
Applications qGraph Software
• Kinetic studies (dissociation- / binding constants)
• Protein interaction (affinity assays)
• Viscosity measurements in microliter volumes
• Cell adhesion / desorption
• Drug effects
• Receptor ligand interactions
• Molecular aggregation
• In situ formation of polymer films
• Enzymatic degradation studies
• Biofilm studies
• Studies of structural changes, proliferation
and cell spreading
• Detection of coagulation status
• Real time studies of antigen-antibody interactions
(e.g. immuno assay, specific coupling of cells
and bacteria, blood typing) The qCell T comes with a complete software suite for fully
• Investigation of the malaria cycle automated instrument control, signal acquisition, real time
(e.g. release and reinvasion of parasites) display, processing and data storage. Individual panels
display frequency, damping (dissipation), temperature and
pump flow profiles. Online protocol commenting, coordinate
display by pick point function, scripts for programming
flow rates, patterns and repetitive cycles can be added and
edited by the operator. Data export to qGraph Viewer,
Excel™, Origin™ and other processing software is supported.
Practical Aspects:
Flow Cell and Sensor Handling
a b c d
Sensor Chip Positioning Closing Operation
Each quartz sensor comes The sensor chip is easily re- The stainless steel flow cell The design of the flow cell
mounted on a thin polymer moved and replaced using a unit is now positioned over guarantees bubble free filling
sensor sheet of precise dimen- pair of tweezers without risk the sensor chip (c) and locked together with uniform and
sions. The sensor chip is labeled of damaging the sensors or with a quarter turn in a reproducible flow dynamics.
with a unique serial number spoiling their surface. It fits bayonet style (d) to complete The filling process as well as
and features an asymmetric accurately, secured against and seal the flow cell, which all situations of measurement
shape with grooves (a) which rotation, into its support can then be filled with sample can be observed visually
precisely fits into a flat cavity at fixture on the qCell / qCell T solution exposing it to the through the optical window
the bottom of the open-archi- and establishes a high quality sensor surface. This design above the sensor surface.
tecture flow cell (b). Different electrical connection. ensures along simple operation After emptying, the flow cell
quartz coatings (e.g. Ti, Ag, high repeatability and quality can be removed without
Cu, Pt, polymers, proteins) are of the sensor signal. risk of contamination of the
available upon request. sensor support fixture.
3qCell / qCell T
Technical Data
Quartz Sensor qCell qCell T
Sensor characteristics Diameter: 8.5 mm, area exposed to liquid 38 mm2, active area 19.6 mm2
Sensor material Quartz, by default coated with gold 1); fixed on mylar sheet
Frequency f0 = 10 MHz
Max. sensitivity for covalent 0.86 ng / Hz 2)
adsorption of sample
Analyte Consumption
Internal volume of flow cell approx. 30 μl (above the sensor)
Minimal sample volume approx. 40 – 80 μl
P3001EN.0913 © 3T analytik Germany · Printed in Germany · Design, form and colour modifications reserved without notice. · Design: haasis.koschera. · Photography: Herbert Härle
Fully automated Fluidic System
Pump Type Peristaltic pump 3) with 12 rollers; flow rates from 9 μl / min up to 5600 μl / min 4)
Materials in contact with liquid PTFE, PEEK, silicone (seal), polyolefin foil, upper quartz electrode
Temperature Control
Temperature control of Peltier system with closed water loop
Temperature range + 4°C to + 80°C
Temperature accuracy 0.1°C (at + 25°C)
Max. speed of cooling 6°C / min
Max. speed of heating 10°C / min
Dimensions, Weight and Connectivity
Dimensions (w x d x h) 100 x 100 x 70 mm3 260 x 317 x 197 mm3
Weight 0.42 kg 6 kg
Interfaces RS 232 or USB Ethernet, TTL I / O,
Interface to control peristaltic pump
1)
Other electrode materials e.g. Ti upon request.
2)
Calculated under the assumption of a flow cell volume of 30 µl.
3)
Included in optional Starter Kit.
4)
Flow rate range depends on the diameter of tubes. Tubing set for pump (Tygon, inside diameter 1 x 0.38 mm and 1 x 1.02 mm) included in optional Starter Kit.
Instruments
smart solutions & service
I GZ Instruments AG Tel. +41 44 456 33 33
Räf felstrasse 32 Fax +41 44 456 33 30
CH – 8045 Zürich www.igz.ch igz@igz.ch
3T GmbH & Co.KG Tel.: +49 (0)7461-165 03 - 0
Gartenstraße 100 Fax: +49 (0)7461-165 03 - 29
D-78532 Tuttlingen E-Mail: info@3t-analytik.de
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